발표논문 및 저서

Refined target-mediated drug disposition modeling of the anti-tissue factor pathway inhibitor antibody MG1113 in cynomolgus monkeys and rabbits

Kwak HC, Jeong YS, Kim JY, Kim MS, Byoun SY, Y Aoki, Chung SJ, Lee W

2026

Frontiers in Pharmacology

Physiologically Based Pharmacokinetic Modeling of Di(2-ethylhexyl) Adipate and Its Primary Metabolite, Mono(2-ethylhexyl) Adipate, in Rats, Incorporating Circulatory Topology-Based Multi-Tissue Metabolism and Lymphatic Absorption

Yang ES, Jeong YS, Kim MS, Kim SC, Chung SJ

2026

Pharmaceutics

In vivo and in vitro assessment of absorption and disposition kinetics of bis[2-(perfluorohexyl)ethyl] phosphate in rats: food effect, physiologically-based modeling, and human exposure estimation

Kim MS, Yang ES, Chung SJ, Lee W, Jeong YS

2026

Environment International

Kinetic modeling of the plasma pharmacokinetic profiles of ADAMTS13 fragment and its Fc-fusion counterpart in mice

Kwak HC, Kim MS, Kim SY, Kim JY, Y Aoki, Chung SJ, Nam HJ, Lee W

2024

Frontiers in Pharmacology

Prediction of the time to reach equilibrium for improved estimation of the unbound fraction of compounds in equilibrium dialysis using kinetic modeling

Bae C, Chung G, Chung SJ

2023

Journal of Pharmaceutical Sciences

Pretreatment of rhesus monkeys with transdermal patches containing physostigmine and procyclidine: implications of the delivery system for the potential application against VX nerve agent intoxication in humans

Nam JH, Kim MS, Song YJ, Kim CH, Kim WS, Yu CH, Joe HE, Hur GH, Seo MR, Kim Y, Park KE, Choi JY, Chung SJ, Shin YK

2023

Archives of Toxicology

Quantification of venadaparib, a novel PARP inhibitor, in the rat and dog plasma using liquid chromatography/tandem mass spectrometry

Lee M, Jang E, Lee J, Choi SK, Lee WS, Baek NS, Lee S, Park YW, Lee JH, Chung SJ

2023

Journal of Analytical Science and Technology

Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans

Lin H, Yoo JW, Roh HJ, Lee MK, Chung SJ, Shim CK and Kim DD

2023

Pharmaceutics

Involvement of CYP3A4 and MDR1 in altered metabolism and transport of indinavir in 1,25(OH)2D3-treated Caco-2 cells

Lee SJ, Joo SA, Kim HJ, Lee YJ, Chung SJ, Chae YJ, Maeng HJ

2023

European Journal of Pharmaceutical Sciences

Determination of the Number of Tissue Groups of Kinetically Distinct Transit Time in Whole-Body Physiologically Based Pharmacokinetic (PBPK) Models II: Practical Application of Tissue Lumping Theories for Pharmacokinetics of Various Compounds

Jeong YS, Kim MS, Chung SJ

2022

The AAPS Journal

Determination of the number of tissue groups of kinetically distinct transit time in whole-body physiologically based pharmacokinetic (PBPK) models I: Theoretical consideration of bottom-up approach of lumping tissues in whole-body PBPK

Jeong YS, Kim MS, Chung SJ

2022

The AAPS Journal

Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans

Kim MS, Lee N, Lee A, Chae YJ, Chung SJ, Lee KR

2022

Pharmaceuticals

Role of the efflux transporters Abcb1 and Abcg2 in the brain distribution of olaparib in mice

Song YK, Kim MJ, Kim MS, Lee JH, Chung SJ, Song JS, Chae YJ, Lee KR

2022

European Journal of Pharmaceutical Sciences

Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics

Lee MJ, Jeong YS, Kim MS, Chung SJ

2022

Pharmaceutics

Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans

Jeong YS, Kim MS, Lee N, Lee A, Chae YJ, Chung SJ, Lee KR

2021

Pharmaceutics

Pharmacokinetic estimation models-based approach to predict clinical implications for CYP induction by calcitriol in human cryopreserved hepatocytes and HepaRG cells

Chae YJ, Kim MS, Chung SJ, Lee MK, Lee KR, Maeng HJ

2021

Pharmaceutics

Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

Jeong YS, Baek M, Lee S, Kim MS, Maeng HJ, Lee JH, Suh YG, Chung SJ

2020

Molecules

Carfilzomib delivery by quinic acid-conjugated nanoparticles: Discrepancy between tumoral drug accumulation and anticancer efficacy in a murine 4T1 orthotopic breast cancer model

Jun Y, Xu J, Kim H, Park JE, Jeong YS, Min JS, Yoon N, Choi JY, Yoo J, Bae SK, Chung SJ, Yeo Y, Lee W

2020

Journal of Pharmaceutical Sciences

Therapeutic efficacy of ABN401, a highly potent and selective MET inhibitor, based o n diagnostic biomarker test in MET-addicted cancer

Kim J, Park KE, Jeong YS, Kim Y, Park H, Nam JH, Jung K, Son WS, Jung HS, Le e JH, Jeong SH, Kim NA, Ha JD, Cho SY, Choi YL, Chung SJ, Choi JY, Hong S, Shin Y K

2020

Cancers

Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats

Song YK, Yoon JH, Woo JK, Kang JH, Lee KR, Oh SH, Chung SJ, Maeng HJ

2020

Pharmaceutics