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서울대학교 약학대학 제2약제학연구실

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  • Jeong, Y. S & Lee, K. R. et al. (2021). Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans , Pharmaceutics, 13(6), 813.
  • Chae, Y. J & Maeng, H. J. et al. (2021). Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells, Pharmaceutics, 13(2), 181.
  • Kim, J. & Shin, Y. K. et al. (2020). Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer , Cancers, 12(6), 1575.
  • Song, Y. K & Maeng, H. J. et al. (2020). Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats, Pharmaceutics, 12(5), 397.
  • Kim, D. G & Lee, B. J. et al. (2020). Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity, Cellular and Molecular Life Sciences, 178, 114053.
  • Park, S. K & Lee, S. K. et al. (2020). A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction, Biochemical Pharmacology, 178, 114053.
  • Jun, Y. & Lee, W. et al. (2020). Carfilzomib Delivery by Quinic Acid-Conjugated Nanoparticles: Discrepancy Between Tumoral Drug Accumulation and Anticancer Efficacy in a Murine 4T1 Orthotopic Breast Cancer Model, Journal of Pharmaceutical Sciences, 109(4), 1615-1622.
  • Jeong, Y. S. & Chung, S. J. et al. (2020). Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry, Molecules, 25(3), 531.
  • Han, S. Y. & Choi, Y. H. et al. (2019). Effect of treatment period with LC478, a disubstituted adamantayl derivative, on P-glycoprotein inhibition: its application to increase docetaxel absorption in rats, Xenobiotica, 1-12.
  • Lee, W. & Lee, B. H. et al. (2019). Z-ligustilide and n-Butylidenephthalide Isolated from the Aerial Parts of Angelica tenuissima Inhibit Lipid Accumulation In Vitro and In Vivo, Planta Medica, 85, 719-728.
  • Jeong, Y. S. & Maeng, H. J. et al. (2019). Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats, Pharmaceutics, 108., 2019
  • Song, Y. K. & Chung, S. J., et al. (2019). Suppression of canine ABCB1 in MDCKII cells unmasks human ABCG2-mediated efflux of olaparib. The Journal of Pharmacology and Experimental Therapeutics, 368, 79-87., 2019
  • Hyung, S., & Chung, S. J. (2018). Identification of the primary determining factor(s) governing the oral absorption of edaravone in rats, European Journal of Pharmaceutical Sciences, 123, 312-320., 2018
  • Oh, Y., & Lee, W. I.,(2018). Inhibition of Organic Anion Transporting Polypeptide 1B1 and 1B3 by Betulinic Acid: Effects of Pre-incubation and Albumin in the Media, Journal of Pharmaceutical Sciences, 2018
  • Son, J. H., & Chung, S. J. (2018). Identification of metabolites of MDR-1339, an inhibitor of β-amyloid protein aggregation, and kinetic characterization of the major metabolites in rats, Journal of Pharmaceutical and Biomedical Analysis, 2018
  • Noh, C. K., & Chung, S. J. (2017). Simultaneous quantification of volitinib and gefitinib in rat plasma by HPLC-MS/MS for application to a pharmacokinetic study in rats. Journal of Separation Science., 2017
  • Hyung, S., & Chung, S. J. (2017). The conditional stimulation of rat organic cation transporter 2, but not its human ortholog, by mesoridazine: the possibility of the involvement of the high-affinity binding site of the transporter in the stimulation, Journal of Pharmacy and Pharmacology, 69(11), 1513-1523., 2017
  • Lee, M. J., & Chung, S. J. (2017). Quantification of IDP-73152, a novel antibiotic, in plasma from mice, rats and humans using an ultra-high performance liquid chromatography/tandem mass spectrometry method for use in pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis., 2017
  • Jeong, Y. S., Chung, S. J. (2017). Estimation of the Minimum Permeability Coefficient in Rats for Perfusion-limited Tissue Distribution in Whole-body Physiologically-based Pharmacokinetics. European Journal of Pharmaceutics and Biopharmaceutics, 2017
  • Ryu, H. M., Chung, S. J. (2017). Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography, tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis., 2017
  • Yim, C. S., & Chung, S. J. (2017). Specific Inhibition of the Distribution of Lobeglitazone to the Liver by Atorvastatin in Rats, Evidence for a Rat Organic Anion Transporting Polypeptide 1B2-Mediated Interaction in Hepatic Transport. Drug Metabolism and Disposition, 45(3), 246-259., 2017
  • Chae, Y. J., Chung, S. J., & Maeng, H. J. (2017). Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T C in the mouse liver. European Journal of Pharmaceutical Sciences, 96, 28-36., 2016
  • Cho, S. J., Kim, D. D. (2016). Effects of Nonalcoholic Fatty Liver Disease on Hepatic CYP2B1 and in Vivo Bupropion Disposition in Rats Fed a High-Fat or Methionine/Choline-Deficient Diet. Journal of Agricultural and Food Chemistry, 64(27), 5598-5606., 2016
  • Lee, J. Y. & Kim, D. D. (2016). Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery. Journal of Controlled Release, 236, 38-46., 2016
  • Lee, J. Y., & Kim, D. D. (2016). Iodinated hyaluronic acid oligomer based nanoassemblies for tumor targeted drug delivery and cancer imaging. Biomaterials, 85, 218~231., 2016
  • Lee, J. Y., & Kim, D. D. (2016). Polyethylene glycol conjugated chondroitin sulfate A derivative nanoparticles for tumor targeted delivery of anticancer drugs. Carbohydrate Polymers, 151, 68~77., 2016
  • Lee, J. Y., & Kim, D. D. (2016). High body clearance and low oral bioavailability of alantolactone, isolated from Inula helenium, in rats: extensive hepatic metabolism and low stability in gastrointestinal fluids. Biopharmaceutics & drug disposition, 37(3), 156-167., 2016
  • Kim, S. B. & Kim, D. D. (2016). Metabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C. Drug Development and Industrial Pharmacy, 2016
  • Lee, J. Y., & Kim, D. D. (2015). Phenylboronic Acid Decorated Chondroitin Sulfate A Based Theranostic Nanoparticles for Enhanced Tumor Targeting and Penetration. Advanced Functional Materials, 25(24), 3705~3717., 2015
  • Lee, J. Y. & Kim, D. D. (2015). Bile acid-conjugated chondroitin sulfate A-based nanoparticles for tumor-targeted anticancer drug delivery. European Journal of Pharmaceutics and Biopharmaceutics, 94, 532-541., 2015
  • Lee, J. H. & Chung, S. J. (2015). The identification of lobeglitazone metabolites in rat liver microsomes and the kinetics of the in vivo formation of the major metabolite M1 in rats. Journal of Pharmaceutical and Biomedical Analysis., 2015
  • Lee, J. H., & Chung, S. J. (2015). Gender Differences in the Hepatic Elimination and Pharmacokinetics of Lobeglitazone in Rats. Biopharmaceutics & drug disposition., 2015
  • Song, K. H., Kim, K. (2015). Paracellular permeation-enhancing effect of AT1002 C-terminal amidation in nasal delivery. Drug Design, Development and Therapy, 9, 1815., 2015
  • Lee, J. H. & Chung, S. J. (2015). Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferato - Activated Receptor Gamma in Rats. Journal of Pharmaceutical Sciences., 2015
  • Kim, Y. C. & Maeng, H. J. (2014). Effects of 1α, 25 Dihydroxyvitamin D3, the Natural Vitamin D Receptor Ligand, on the Pharmacokinetics of Cefdinir and Cefadroxil, Organic Anion Transporter Substrates, in Rat. Journal of pharmaceutical sciences, 103(11), 3793-3805., 2014
  • Kim, S. B. & Kim, D. D. (2014). In vitro and in vivo evaluation of the effect of puerarin on hepatic cytochrome p450-mediated drug metabolism. Planta medica, 80(7), 561-567., 2014
  • Jahn, A. & Kim, D. D. (2014). AAPE proliposomes for topical atopic dermatitis treatment. Journal of microencapsulation, 31(8), 768-773., 2014
  • Han, Y. T & Suh, Y. G. (2014). Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE). European journal of medicinal chemistry, 79, 128-142., 2014
  • Kim, K. S & Shim, C. K. (2013). Smooth muscle relaxation activity of an aqueous extract of dried immature fruit of Poncirus trifoliata (PF-W) on an isolated strip of rat ileum. Natural product communications, 8(8), 1143-1148., 2013
  • Jung, E. & Kim, D. D. (2013). Effect of permeation enhancers on transdermal delivery of fluoxetine: In vitro and in vivo evaluation. International journal of pharmaceutics, 456(2), 362-369., 2013
  • Son, Y. J. & Kim, D. D. (2013). Porous hyaluronic acid/sodium alginate composite scaffolds for human adipose-derived stem cells delivery. International journal of biological macromolecules, 61, 175-181., 2013
  • Park, J. H. & Shim, C. K. (2013). Chitosan microspheres as an alveolar macrophage delivery system of ofloxacin via pulmonary inhalation. International journal of pharmaceutics, 441(1), 562-569., 2013
  • Termsarasab, U. & Kim, D. D. (2013). Chitosan oligosaccharide arachidic acid-based nanoparticles for anti cancer drug delivery. International journal of pharmaceutics, 441(1), 373-380., 2013
  • Jin, H. E. & Shim, C. K. (2013). Transport of gemifloxacin, a 4th generation quinolone antibiotic, in the Caco-2 and engineered MDCKII cells, and potential involvement of efflux transporters in the intestinal absorption of the drug. Xenobiotica, 43(4), 355-367., 2013
  • Chae, Y. J. & Chung, S. J. (2012). Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population. Journal of pharmaceutical sciences, 101(3), 1302-1313., 2012
  • Kim, J. E. & Kim, D. D. (2012). The limited intestinal absorption via paracellular pathway is responsible for the low oral bioavailability of doxorubicin. Xenobiotica, 43(7), 579-591., 2012
  • Jin, Y. J. & Kim, D. D. (2012). Hyaluronic acid derivative-based self-assembled nanoparticles for the treatment of melanoma. Pharmaceutical research, 29(12), 3443-3454., 2012
  • Yoon, I. & Kim, D. D. (2012). Saturable sinusoidal uptake is rate-determining process in hepatic elimination of docetaxel in rats. Xenobiotica, 42(11), 1110-1119., 2012
  • Maeng, H. J. & Chung, S. J. (2012). Functional impairment of P-glycoprotein by sodium nitroprusside pretreatment in mouse brain capillary endothelial cells. Archives of pharmacal research, 35(7), 1215-1221., 2012
  • Song, C. K. & Kim, D. D. (2012). A novel vesicular carrier, transethosome, for enhanced skin delivery of voriconazole: Characterization and in vitro/in vivo evaluation. Colloids and Surfaces B: Biointerfaces, 92, 299-304., 2012
  • Song, C. K. & Kim, D. D. (2012). In vitro and in vivo evaluation of N, N, N trimethylphytosphingosine iodide (TMP) in liposomes for the treatment of angiogenesis and metastasis. International journal of pharmaceutics, 434(1), 191-198., 2012
  • Maeng, H. J. & Chung, S. J. (2012). Differential changes in functional activity of organic cation transporters in rats with uranyl nitrate-induced acute renal failure. Archives of pharmacal research, 35(8), 1441-1448., 2012
  • Kwak, E. Y. & Shim, C. K. (2012). Enhanced intracellular accumulation of a non-nucleoside anti-cancer agent via increased uptake of its valine ester prodrug through amino acid transporters. Xenobiotica, 42(7), 603-613., 2012
  • Koo, T. S. & Chong, S. (2012). Functional impairment of rat taurine transporter by activation of nitrogen oxide through superoxide. Drug metabolism and pharmacokinetics, 27(3), 286-293., 2012
  • Cho, H. J & Kim, D. D. (2012). Poly-L-arginine and dextran sulfate-based nanocomplex for epidermal growth factor receptor (EGFR) siRNA delivery: its application for head and neck cancer treatment. Pharmaceutical research, 29(4), 1007-1019., 2012
  • Chang, J. E. & Shim, C. K. (2012). Liver cancer targeting of doxorubicin with reduced distribution to the heart using hematoporphyrin-modified albumin nanoparticles in rats. Pharmaceutical research, 29(3), 795-805., 2012
  • Lee, K. R. & Chung, S. J. (2012). Quantification of cilnidipine in human plasma by liquid chromatography mass spectrometry. Journal of liquid chromatography & related technologies, 35(2), 308-320., 2012
  • Ku, W. S. & Kim, D. D. (2011). Rapid and sensitive determination of udenafil in plasma by LC-MS/MS for intranasal pharmacokinetic study in rats. Chemical and Pharmaceutical Bulletin, 59(9), 1083-1088., 2011
  • Lee, K. R. & Chung, S. J. (2011). A strategy for reducing particulate contamination on opening glass ampoules and development of evaluation methods for its application. Drug development and industrial pharmacy, 37(12), 1394-1401., 2011
  • Lee, K. R. & Chung, S. J. (2011). Physiologically based pharmacokinetic modeling of SNU-0039, an anti Alzheimer’s agent, in rats. Journal of pharmacokinetics and pharmacodynamics, 38(5), 637-651., 2011
  • Evaluation of protein stability and in vitro permeation of lyophilized polysaccharides-based microparticles for intranasal protein delivery. Hyun-Jong Cho, Prabagar Balakrishnan, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. International Journal of Pharmaceutics. 416(1), pp.77-84., 2011
  • Enhanced in vitro cellular uptake of P-gp substrate by poloxamer-modified liposomes (PMLs) in MDR cancer cells. Chung Kil Song, Prabarga Balakrishnan, Chang-Koo Shim, Suk-Jae Chung, Dae-Duk Kim. Journal of Microencapsulation. 28(6), pp.575-581., 2011
  • Expression and functional activity of P-glycoprotein in passaged primary human nasal epithelial cell monolayers cultured by the air-liquid interface method for nasal drug transport study. Hyun-Jong Cho, Min-Koo Choi, Hongxia Lin, Jung Sun Kim, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. Journal of Pharmacy and Pharmacology. 63(3), pp.385-391., 2011
  • Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol. In-Soo Yoon, Min-Koo Choi, Jung Sun Kim, Chang-Koo Shim, Suk-Jae Chung, Dae-Duk Kim. Xenobiotica. 41(3), pp.243-251, 2011
  • Determination of zabofloxacin in rat plasma by liquid chromatography with mass spectrometry and its application to pharmacokinetic study. Hyo-Eon Jin, Kyeong-Ryoon Lee, In-Hyul Kang, Suk-Jae Chung, Chang-Koo Shim. Journal of Pharmaceutical and Biomedical Analysis. 54(4), pp.873-877, 2011
  • Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride. Journal of Pharmaceutical Sciences. Hyun-Jong Cho, Prabagar Balakrishnan, Eun-Kyoung Park, Ki-Won Song, Soon-Sun Hong, Tae-Young Jang, Kyu-Sung Kim, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. 100(2), pp.681-691, 2011
  • Kim, M. H. & Chung, S. J. (2010). Evidence of carrier mediated transport in the penetration of donepezil into the rat brain. Journal of pharmaceutical sciences, 99(3), 1548-1566., 2010
  • Chung, S. J. (2010). Oral bioavailability of new drug leads is a challenge for pharmaceutical scientists. Arch Pharm Res. 2010 May;33(5):645, 2010
  • Chung, S. J. (2010). Challenges for Kinetic Identification of Variability Associated with Genetic Polymorphisms of Transporters. Drug metabolism and pharmacokinetics, 25(5), 409-410., 2010
  • Preparation and evaluation of fexofenadine microemulsions for intranasal delivery. Hong-Mei Piao, Prabagar Balakrishnan, Hyun-Jong Cho, yunjun Kim, You-Sun Kim, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. International Journal of Pharmaceutics. 395 (2010) 309-316., 2010
  • Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride. Yeamin Huh, Hyun-Jong Cho, In-Soo Yoon, Min-Koo Choia, Jung Sun Kimc, Euichaul Ohd, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. European Journal of Pharmaceutical Sciences. 40(2010) 9-15, 2010
  • The effects of mixed MPEG-PLA/Pluronic(R) copolymer micelles on the bioavailability and multidrug resistance of docetaxel. Chao-Feng Mua, Prabagar Balakrishnan, Fu-De Cui, Yong-Mei Yin, Yong-Bok Lee, Han-Gon Choi, Chul Soon Yong, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. Biomaterials. 31(8):2371-2379., 2010
  • Characterization and in vitro evaluation of freeze-dried microparticles composed of granisetron-cyclodextrin complex and carboxymethylcellulose for intranasal delivery. Hyun-Jong Cho, Prabagar Balakrishnan, Won-Sik Shim, Suk-Jae Chung, Chang-Koo Shim, Dae-Duk Kim. International Journal of Pharmaceutics. 400(1-2):59-65, 2010
  • Lee, K. R. & Chung, S. J. (2010). Lack of a primary physicochemical determinant in the direct transport of drugs to the brain after nasal administration in rats: potential involvement of transporters in the pathway. Drug metabolism and pharmacokinetics, (0), 1009240045., 2010
  • Lee, K. R. & Chung, S. J. (2010). Simultaneous determination of artesunate and dihydroartemisinin concentrations in human plasma by high performance liquid chromatography-mass spectrometry with electro-spray ionization. Analytical Letters, 43(2), 226-239., 2010
  • Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its application to pharmacokinetic studies.J.H. Lee, Y.A. Woo, I.C. Hwang, C.Y. Kim D.D. Kim, C.K. Shim and S.J. Chung. J. Pharm. Biomed. Anal., 50(5), 872-877., 2009
  • Contribution of a significant first-pass effect of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in the liver to its poor bioavailability in rats.K.H. Yu, Y.R. Lee, S.H. Ahn, D.D. Kim, C.K. Shim and S.J. Chung. J. Pharm. Pharmacol., 61(9), 1197-1203., 2009
  • Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation. Y.M. Yin, F.D. Cui, C.F. Mu. M.K. Choi, J.S. Kim, S.J. Chung, C.K. Shim and D.D. Kim. J. Cont. Rel., 140, 86-94., 2009
  • Tissue-specific changes in mRNA expression of Abc and Slc transporters in murine pulmonary tuberclosis. S.H. Lee, T. Oh, B.Y. Jeon, E.Y. Kwak, W.S. Shim, S.N. Cho, D.D. Kim, S.J. Chung and C.K. Shim. Xenobiotica., 39(10), 738-748., 2009
  • Decreased urinary secretion of belotecan in folic acid-induced acute renal failuree rats due to down-regulation of Oat1 and Bcrp. Q.R. Jin, W.S. Shim, M.K. Choi, G.Y. Tian, I.S. Song, S.G. Yang, D.D. Kim, S.J. Chung, C.K. Shim. Xenobiotica., 39(10), 11-21., 2009
  • Preparation, characterization and in vivo intestinal absorption of a dry emulsion formulation containing atorvastatin calcium. Y.M. Yin, F.D. Cui, J.S. Kim, M.K. Choi, B.C. Choi, S.J. Chung, C.K. Shim, D.D. Kim. Drug Delivery., 16(1) 30-36., 2009
  • Synergic enhancing-effect of DEET and dodecylamine on the skin permetion of testosterone from a matrix-type transdermal delivery system. H. Zhao, M.K. Choi, J.S. Kim, C.S, Yong, H.G. Choi, S.J. Chung, C.K. Shim, D.D. Kim. Drug Delivery., 16(5) 249-253., 2009
  • Determination of belotecan in the plasma, bile, and urine of rats by high-performance liquid chromatography with fluorescence detection and its application to a pharmacokinetic study. Q.R. Jin, I.W. Kim, M.K. Choi, W.S. Shim,G.Y. Tian, S. Lee, J. Lee, D.D. Kim, S.J. Chung, and C.K. Shim. Analytical Letters., 42: 68-83., 2009
  • Novel porous matrix of hyaluronic acid for the three-dimensional culture of chondrocytes. Kang JY, Chung CW, Sung JH, Park BS, Choi JY, Lee SJ, Choi BC, Shim CK, Chung SJ, Kim DD. Int J Pharm., 369, 114-120., 2009
  • Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor. Yang R, Shim WS, Cui FD, Cheng G, Han X, Jin QR, Kim DD, Chung SJ, Shim CK. Int. J. Pharm., 371, 142-147., 2009
  • Testosterone-independent down-regulation of Oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: effects on distribution of a model organic cation, tetraethylammonium. Shim WS, Park JH, Ahn SJ, Han L, Jin QR, Li H, Choi MK, Kim DD, Chung SJ and Shim CK. J. Pharm. Sci., 98(2):739-747., 2009
  • Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates. Yang R, Yang SG, Shim WS, Cui F, Cheng G, Kim IW, Kim DD, Chung SJ and Shim CK. J. Pharm. Sci., 98(3):970-984., 2009
  • Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-Induced cholestasis. Jin HE, Hong SS, Choi MK, Maeng HJ, Kim DD, Chung SJ and Shim CK. Pharm. Res., 26(3):549-559., 2009
  • Involvement of P-glycoprotein, Multidrug Resistance Protein 2 and Breast Cancer Resistance Protein in the Transport of Belotecan and Topotecan in Caco-2 and MDCKII Cells. Hong Li, Hyo-Eon Jin, Wooyoung Kim, Yong-Hae Han, Dae-Duk Kim, Suk-Jae Chung, and Chang-Koo Shim. Pharm Res., 25(11):2601-12., 2008
  • Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis. S.M. Hwang, D.D. Kim, S.J. Chung, C.K. Shim. J Control Release., 129(2):100-6., 2008
  • Effect of ion-pair formation with bile salts on the in vitro cellular transport of berberine. Chae HW, Kim IW, Jin HE, Kim DD, Chung SJ, Shim CK. Arch Pharm Res., 31(1):103-10., 2008
  • Skin permeation enhancement of diclofenac by fatty acids. Min-Jung Kim; Hea-Jeong Doh; Min-Koo Choi; Suk-Jae Chung; Chang-Koo Shim; Dae-Duk Kim; Jung Sun Kim; Chul-Soon Yong; Han-Gon Choi. Drug Deliv., 15(6):373-9., 2008
  • Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract. Won-Sik Shim, Min-Koo Choi, In-Wha Kim, Tae-Sik Kwon, Im-Sook Song1, Liwei Han2, Dae-Duk Kim, Suk-Jae Chung, and Chang-Koo Shim. Arch Pharm Res., 31(5):671-7., 2008
  • Pharmacokinetics and pharmacodynamics of ketoprofen plasters. Sung-Koun Heo, Jeiwon Cho, Ji-Woong Cheon, Min-Koo Choi, Dong-Soon Im, Jung Ju Kim, Yang Gyu Choi, Do Yong Jeon, Suk-Jae Chung, Chang-Koo Shim and Dae-Duk Kim. Biopharm Drug Dispos., 29(1):37-44., 2008
  • Functional Induction of P-glycoprotein in the Blood Brain Barrier of Streptozotocin-induced Diabetic Rats: Evidence for the Involvement of NF-κB, a Nitrosative Stress-sensitive Transcription Factor, in the Regulation. Maeng HJ, Kim MH, Jin HE, Shin SM, Tsuruo T, Kim SG, Kim DD, Shim CK, Chung SJ. Drug Metab Dispos. 35(11), 1996-2005., 2007
  • Liposome formulation of Paclitaxel with enhanced solubility and stability. Yang T, Cui FD, Choi MK, Lin H, Chung SJ, Shim CK, Kim DD. Drug Deliv.,14(5):301-8., 2007
  • Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome. Yang T, Choi MK, Cui FD, Kim JS, Chung SJ, Shim CK, Kim DD. J Control Release. 2007 Jul 31;120(3):169-77. Epub 2007 May 17., 2007
  • Enhanced solubility and stability of PEGylated liposomal paclitaxel: in vitro and in vivo evaluation. Yang T, Cui FD, Choi MK, Cho JW, Chung SJ, Shim CK, Kim DD. Int J Pharm.,338(1-2):317-26., 2007
  • Air-liquid interface (ALI) culture of human bronchial epithelial cell monolayers as an in vitro model for airway drug transport studies. Lin H, Li H, Cho HJ, Bian S, Roh HJ, Lee MK, Kim JS, Chung SJ, Shim CK, Kim DD. J Pharm Sci.,96(2):341-50., 2007
  • Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer. Lin H, Gebhardt M, Bian S, Kwon KA, Shim CK, Chung SJ, Kim DD. Int J Pharm.,330(1-2):23-31., 2007
  • The transport of organic cations in the small intestine: current knowledge and emerging concepts. Kim MK, Shim CK. Arch Pharm Res.,29(7):605-16. Review., 2006
  • Application of a sample pooling method for the accelerated assessment of the rate of uptake of drugs by the brain in rats. Kim KP, Ahn SH, Sung JH, Koo TS, Byun MJ, Kim DD, Shim CK, Chung SJ. J Pharm Pharmacol.,58(6):837-46., 2006
  • Stable bioavailability of cyclosporin A, regardless of food intake, from soft gelatin capsules containing a new self-nanoemulsifying formulation. Yang SG, Kim DD, Chung SJ, Shim CK. Int J Clin Pharmacol Ther.,44(5):233-9., 2006
  • Altered pharmacokinetics and hepatic uptake of TBuMA in ethynylestradiol-induced cholestasis. Hong SS, Choi JM, Jin HE, Shim CK. Arch Pharm Res.,29(4):323-7., 2006
  • Mechanism of intestinal transport of an organic cation, tributylmethylammonium in Caco-2 cell monolayers. Hong SS, Moon SC, Shim CK. Arch Pharm Res.,29(4):318-22., 2006
  • Quantification of clotiazepam in human plasma by gas chromatography-mass spectrometry. Ahn SH, Maeng HJ, Koo TS, Kim DD, Shim CK, Chung SJ. J Chromatogr B Analyt Technol Biomed Life Sci.,834(1-2):128-33., 2006
  • Clinical pharmacokinetics of oxaliplatin and 5-fluorouracil administered in combination with leucovorin in Korean patients with advanced colorectal cancer. Cho HK, Lee ES, Lee JW, Park JK, Kang JH, Lee KS, Shim CK, Chung SJ, Kim DD, Kuh HJ. J Cancer Res Clin Oncol., 132(5):320-6., 2006
  • Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer. Lin H, Yoo JW, Roh HJ, Lee MK, Chung SJ, Shim CK, Kim DD. Eur J Pharm Sci.,26(2):203-10., 2005
  • Effect of nonylphenol ethoxylates (NPEs) on barrier functions of epithelial cell membranes: opening of tight junctions and competitive inhibition of P-gp-mediated efflux. Doo MH, Li H, Jang HI, Song IS, Chung SJ, Shim CK. Int J Pharm.,302(1-2):145-53., 2005
  • Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer. Hongxia Lin, Jin-Wook Yoo, Hwan-Jung Roh, Min-Ki Lee, Suk-Jae Chung, Chang-Koo Shim and Dae-Duk Kim Eur. J. Pharm. Sci., 26(2):203-10, 2005
  • Saturable distribution of tacrine into the striatal extracellular fluid of the rat: evidence of involvement of multiple organic cation transporters in the transport. Jong-Hyuk Sung, Kyung-Ha Yu, Jin-Sun Park, Takashi Tsuruo, Dae-Duk Kim, Chang-Koo Shim, and Suk-Jae Chung Drug Metab. Dispos., 33(3):440-8, 2005
  • Prokinetic activity of an aqueous extract from dried immature fruit of Poncirus trifoliata (L.) Raf. Hyun-Tai Lee, Eun-Kyoung Seo, Suk-Jae Chung and Chang-Koo Shim J. Ethnopharmacol., Epub ahead of print, 2005
  • Mechanism of the stationary canalicular excretion of tributylmethyl ammonium in rats with a CCl4-induced acute hepatic injury. M.K. Choi, I.S. Song, S.R. Park, S.S. Hong, D.D. Kim, S.J. Chung(*), C.K. Shim J. Pharm. Sci., 94(2):317-326, 2005
  • Limited Role of P-Glycoprotein in the Intestinal Absorption of Cyclosporin A. Y.J. Lee, S.J. Chung, C.K. Shim(*) Biol. Pharm. Bull., 28(4):760-763, 2005
  • In vitro and in vivo evaluation of a novel nonscrotal matrix-type transdermal delivery system of testosterone. Zhao H., Lee C.H., Chung S.J., Shim C.K., Kim D.D. Drug Dev. Ind. Pharm., 31(3):257-61, 2005
  • Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts. Keon-Hyoung Song, Suk-Jae Chung, and Chang-Koo Shim J. Control. Release., 106(3):298-308, 2005
  • Effect of a New Hepatoprotective Agent, YH-439, on the Hepatobiliary Transport of Organic Cations (OCs): Selective Inhibition of Sinusoidal OCs Uptake without Influencing Glucose Uptake and Canalicular OCs Excretion Soon-Sun Hong, Hong Li, Min-Koo Choi, Suk-Jae Chung, and Chang-koo Shim Archives of Pharmacal Research, 28:330-334, 2005
  • Effect of an aqueous extract of dried immature fruit of Poncirus trifoliata (L.) Raf. on intestinal transit in rodents with experimental gastrointestinal motility dysfunctions. Hyun-Tai Lee, Eun-Kyoung Seo, Suk-Jae Chung and Chang-Koo Shim J. Ethnopharmacol., 2005
  • Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: Association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium. Moon Kyoung Kim, Liwei Han, Min Koo Choi, Yong-Hae Han, Dae-Duk Kim, Suk-Jae Chung, Chang-Koo Shim J Pharm Sci., 94(12):2644-55, 2005
  • Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: Evidence for extrahepatic metabolism. Tae-Sung Koo, Dae-Hyun Kim, Sung-Hoon Ahn, Kang-Pil Kim, In-Wha Kim, Seung-Yong Seo, Young-Ger Suh, Dae-Duk Kim, Chang-Koo Shim, and Suk-Jae Chung J. Pharm. Sci., 94(10):2187-97, 2005
  •  Su‐Geun Yang, So‐Ra Park, Dae‐Duk Kim, Suk‐Jae Chung & Chang‐Koo Shim (2006) A Simple HPLC Method for the Determination of Cyclosporin A in Human Whole Blood, Journal of Liquid Chromatography & Related Technologies, 29:3, 391-401, DOI: 10.1080/10826070500452010
  • Advanced Formulation and Pharmacological Activity of Hydrogel of the Titrated Extract of C. Asiatica. Soon-Sun Hong, Jong-Ho Kim, Hong Li, and Chang-Koo Shim Archives of Pharmacal Research, 28(4):502-508, 2005
  • Osteosarcoma presenting as an aggressive nodular mass in the region of the mandible. Ong ST, Shim CK, Ng KH, Siar CH. J Oral Sci.,46(1):55-9., 2004
  • Pharmacokinetic characterization of dehydroevodiamine in the rat brain. Sung-Hoon Ahn, Seng-Ho Jeon, Takashi Tsuruo, Chang-Koo Shim, Suk-Jae Chung(*) J. Pharm. Sci., 93(2):283-92, 2004
  • Effects of cysteine on the poharmacokinetics intravenous torasemide in rats with protein-calorie malnutrition. S.K. Bae, D.Y. Lee, A.K. Lee, J.W. Kwon, I.Lee, S.J. Chung, S.G. Kim, C.K. Shim, M.G. Lee(*) J. Pharm. Sci., 93(9):2388-2398, 2004
  • The suppressed expression and functional activity of hepatic P-glycoprotein in rats with protein-calorie malnutrition. Y.M. Lee, I.S. Song, S.G. Kim, M.G. Lee, S.J. Chung, C.K Shim(*) J. Pharm. Sci., 92(7):1323-1330, 2003
  • Multiple alterations of canalicular membrane transport activities in rats with CCl4-induced hepatic injury. Im-Sook Song, Young-Mi Lee, Suk-Jae Chung, and Chang-Koo Shim Drug Metab. Dispos., 31(4):482-90, 2003
  • Kinetic analysis about the bidirectional transport of 1-anilino-8-naphthalene sulfonate (ANS) by isolated rat hepatocytes. Lee P.S., Song I.S., Shin T.H., Chung S.J., Shim C.K., Song S., Chung Y.B. Arch. Pharm. Res., 26(4):338-43, 2003
  • Enhanced Oral Bioavailability of Paclitaxel by Coadministration of the P-Glycoprotein Inhibitor KR30031. Jong Soo Woo, Chang Hyun Lee, Chang Koo Shim and Sung-Joo Hwang Pharm Res., 20(1):24-30, 2003
  • Effects of cysteine on the pharmacokinetics of itraconazole in rats with protein-calorie malnutrition. Ae K. Lee, Choong Y. Ahn, Eun J. Kim, Jong W. Kwon, Sang G. Kim, Suk J. Chung, Chang-K. Shim, Myung G. Lee Biopharm Drug Dispos., 24(2):63-70, 2003
  • Effects of cysteine on the pharmacokinetics of intravenous clarithromycin in rats with protein-calorie malnutrition. Choong Y. Ahn, Eun J. Kim, Jong W. Kwon, Suk J. Chung, Sang G. Kim, Chang-K. Shim and Myung G. Lee Life Sci., 73(14):1783-94, 2003
  • Effect of excipients on the stability and transport of recombinant human epidermal growth factor (rhEGF) across Caco-2 cell monolayers. Kim IW, Yoo HJ, Song IS, Chung YB, Moon DC, Chung SJ, Shim CK Arch. Pharm. Res., 26(4):330-7, 2003
  • Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers. Im-Sook Song, Yong-Hae Han, Suk-Jae Chung and Chang-Koo Shim Pharm. Res., 20(4):597-604, 2003
  • Small intestinal transit does not adequately represent postoperative paralytic ileus in rats. Lee H.T., Chung S.J., Shim C.K. Arch. Pharm. Res., 25(6):978-83, 2002
  • Simple liquid chromatography-electrospray ionization mass spectrometry method for the routine determination of salmon calcitonin in serum. Keon-Hyoung Song, Heung-Man An, Hack-Joo Kim, Sung-Hoon Ahn, Suk-Jae Chung and Chang-Koo Shim J. Chromatogr. B Analyt. Technol. Biomed Life Sci., 775(2):247-55, 2002
  • Preparation and evaluation of proliposomes containing salmon calcitonin. Keon-Hyoung Song, Suk-Jae Chung and Chang-Koo Shim J. Control. Release., 84(1-2):27-37, 2002
  • P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers. Han-Joo Maeng, Ho-Jung Yoo, In-Wha Kim, Im-Sook Song, Suk-Jae Chung, Chang-Koo Shim J. Pharm. Sci., 91(12):2614-21, 2002
  • Mechanism of the Reduced Elimination Clearance of Benzylpenicillin from Cerebrospinal Fluid in Rats with Intracisternal Administration of Lipopolysaccharide. Hee Han, Sang-Geon Kim, Myung-Gull Lee, Chang-Koo Shim, and Suk-Jae Chung Drug Metab. Dispos., 30(11):1214-20, 2002
  • Identification of genes enhanced by protein-calorie malnutrition by differential display polymerase chain reaction (expression of fibrinogen B beta chain, B cell translocation gene 1 and thyroid hormone responsive protein genes). Ae Kyung Lee, Keon Wook Kang, Yoon Gyoon Kim, Min Kyung Cho, Myung Gull Lee, Chang-Koo Shim, Suk Jae Chung and Sang Geon Kim Mol. Cell. Biochem., 231(1-2):163-71, 2002
  • Hepatobiliary excretion of tributylmethylamonium in rats with lipopolysaccharide-induced acute inflammation. Lee I.K., Lee Y.M., Song I.S., Chung S.J., Kim S.G., Lee M.G., Shim C.K. Arch. Pharm. Res., 25(6):969-72, 2002
  • Effect of nitric oxide on the sinusoidal uptake of organic cations and anions by isolated hepatocytes. Song, I.S., Lee, I.K., Chung, S.J., Kim, S.G., Lee, M.G., Shim, C.K. Arch. Pharm. Res., 25(6):984-8, 2002
  • Effects of cysteine on the pharmacokinetics of intravenous chlorzoxazone in rats with protein-calorie malnutrition. Yoon G. Kim, Min K. Cho, Jong W. Kwon, Sang G. Kim, Suk J. Chung, Chang-K. Shim, Myung G. Lee Biopharm. Drug Dispos., 23(3):121-9, 2002
  • Characterization of the Transport of Uracil Across Caco-2 and LLC-PK1 Cell Monolayers. Hong Li, Suk-Jae Chung and Chang-Koo Shim Pharm. Res., 19(10):1495-501, 2002
  • Altered metabolism of orally administered loxoprofen in human subjects after an oral administration of loxoprofen for three consecutive days followed by a seven-day washout. In-Wha Kim, Suk-Jae Chung, Chang-Koo Shim J. Pharm. Sci., 91(4):973-9, 2002
  • The transport of a reversible proton pump antagonist, 5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinoli ne-2-yl) pyrimidine hydrochloride (YH1885), across Caco-2 cell monolayers. Li H., Chung S.J., Kim D.C., Kim H.S., Lee J.W., Shim C.K. Drug Metabolism and Disposition, 29(1):54-59, 2001
  • The Transport of a Hepatoprotective Agent Isopropryl 2-(1-3- dithiethane-2-ylidene)-2[N-(4-methyl-thiazole-2-yl) carbamoyl] Acetate (YH439), across Caco-2 Cell Monolayers. Park H.W., Chung S.J., Lee M.G., Shim C.K. Archives of Pharmacal Research, 24(6):584-589, 2001
  • The prevention of cyclosporin A adsorption to Transwell® surfaces by human plasma. Lee Y.J., Chung S.J., Shim C.K. International Journal of Pharmaceutics, 224(1-2):201-204, 2001
  • Simultaneous determination of loxoprofen and its diastereomeric alcohol metabolites in human plasma and urine by a simple HPLC-UV detection method. Choo K.S., Kim I.W., Jung J.K., Suh Y.G., Chung S.J., Lee M.H., Shim C.K. Journal of Pharmaceutical and Biomedical Analysis, 25(3-4):639-650, 2001
  • Preparation of 153Sm-chitosan complex for radiation synovectomy. Shin B.C., Park K.B., Jang B.S., Lim S.M., Shim C.K. Nuclear medicine and biology, 28(6):719-725, 2001
  • Nasal absorption of procyclidine in rats and dogs. Jang E.J., Lee Y.J., Chung S.J., Shim C.K. Archives of Pharmacal Research, 24(3):219-223, 2001
  • Enhanced skin permeation of a new capsaicin derivative (DA-5018) from a binary vehicle system composed of isopropyl-myristate and ethoxydiglycol. Cha B.J., Lee E.D., Kim W.B., Chung S.J., Lee M.H., Shim C.K. Archives of Pharmacal Research, 24(3):224-228, 2001
  • Effects of cysteine on the pharmacokinetics of intravenous phenytoin in rats with protein-calorie malnutrition. Kim Y.G., Cho M.K., Kwon J.W., Kim S.G., Chung S.J., Shim C.K., Lee M.G. International Journal of Pharmaceutics, 229(1-2):45-55, 2001
  • Different pharmacokinetics of nicotine following intravenous administration of nicotine base and nicotine hydrogen tartarate in rats. Jung B.H., Chung B.C., Chung S.J., Shim C.K. Journal of Controlled Release, 77(3):183-190, 2001
  • Contribution of ion pair complexation with bile salts to biliary excretion of organic cations in rats. Song I.S., Chung, S.J., Shim C.K. American Journal of Physiology - Gastrointestinal and Liver Physiology, 281(2 44-2):G515-G525, 2001
  • Bioequivalence of two aceclofenac tablet formulations after a single oral dose to healthy male Korean volunteers. Kim Y.G., Lee Y.J., Kim H.J., Lee S.D., Kwon J.W., Kim W.B., Shim C.K., Lee M.G. International Journal of Clinical Pharmacology and Therapeutics, 39(2):83-88, 2001
  • The potential replacement of HPLC by 125I-RIA for the characterization of cyclosporin A: a bioavailability study after oral administration in healthy human subjects. Young-Joo Lee, Suk-Jae Chung and Chang-Koo Shim J. Pharm. Biomed. Anal., 22(1):183-8, 2000
  • Prolonged delivery of nicotine in rats via nasal administration of proliposomes. Byung Hwa Jung, Bong Chul Chung, Suk-Jae Chung, Min-Hwa Lee and Chang-Koo Shim J. Control. Release., 66(1):73-9, 2000
  • Functional Impairment of Sinusoidal Membrane Transport of Organic Cations in Rats with CCl4-Induced Hepatic Failure. Soon-Sun Hong, Suk-Jae Chung and Chang-Koo Shim Pharm. Res., 17(7):833-8, 2000
  • Effect of prokinetic agents, cisapride and metoclopramide, on the bioavailability in humans and intestinal permeability in rats of ranitidine, and intestinal charcoal transit in rats. Lee H.T., Lee Y.J., Chung S.J., Shim C.K. Research Communications in Molecular Pathology and Pharmacology, 108(5-6):311-323, 2000
  • Decreased oral bioavailability of loxoprofen at second administration in human subjects. Kim I.W., Choo K.S., Han T.G., Kim K.S., Chung S.J., Lee M.H., Shim C.K. Int. J. Clin. Pharmacol. Ther., 38(1):10-4, 2000
  • Bioequivalence assessment of closerin capsule to dura seromycin capsule of cycloserine after a single oral dose administration to healthy male volunteers. Kim Y.G., Lee Y.J., Lee E.D., Lee S.D., Kwon J.W., Kim W.B., Shim C.K., Lee M.G. Int. J. Clin. Pharmacol. Ther., 38(10):461-6, 2000
  • Different activity of ATP dependent transport across the canalicular membrane for tributylmethylammonium and triethylmethylammonium as a potential mechanism of the preferential biliary excretion for tributylmethylammonium in the rat. Song IS, Chung SJ, Shim CK. Pharm Res.,16(4):540-4., 1999
  • Simultaneous GC-MS determination of nicotine and cotinine in plasma for the pharmacokinetic characterization of nicotine in rats. Byung-Hwa Jung, Bong-Chul Chung, Suk-Jae Chung, Min-Hwa Lee and Chang-Koo Shim J. Pharm. Biomed. Anal., 20(1-2):195-202, 1999
  • Canalicular membrane transport is primarily responsible for the difference in hepatobiliary excretion of triethylmethylammonium and tributylmethylammonium in rats. Yong-Hae Han, Suk-Jae Chung, and Chang-Koo Shim Drug Metab. Dispos., 27(8):872-9, 1999
  • Species differences in pharmacokinetics of a hepatoprotective agent, YH439, and its metabolites, M4, M5, and M7, after intravenous and oral administration to rats, rabbits, and dogs. Woo-H. Yoon, Jung-K. Yoo, Jong-W. Lee, Chang-K. Shim, and Myung-G. Lee Drug. Metab. Dispos., 26(2):152-63, 1998
  • Simultaneous determination of a new hepatoprotective agent, YH439, and its metabolites, M4, M5, and M7 in plasma and urine by high-performance liquid chromatography. Yoon W.H., Yoo J.K., Lee J.W., Shim C.K., Lee M.G. Res. Commun. Mol. Pathol. Pharmacol., 99(1):117-24, 1998
  • Delivery of hydrocortisone from liposomal suspensions to the hairless mouse skin following topical application under non-occlusive and occlusive conditions. Kim M.K., Chung S.J., Lee M.H., Shim C.K. J. Microencapsul., 15(1):21-9, 1998
  • Bioequivalence of Neoplanta capsule to Sandimmune Neoral, microemulsion formulations of cyclosporin A in human subjects. Lee Y.J., Chung S.J., Shim C.K. Int. J. Clin. Pharmacol. Ther., 36(4):210-5, 1998
  • Accelerated oral absorption of gliclazide in human subjects from a soft gelatin capsule containing a PEG 400 suspension of gliclazide. S.S. Hong, S.H. Lee, Y.J. Lee, S.J. Chung, M.H. Lee and C.K. Shim J. Control. Release., 51(2-3):185-92., 1998
  • Pharmacokinetics of 1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1- piperazinyl)-1,4-dihydro-4-oxoquinolone-3-carboxylic acid hydrochloride (DW-116), a new quinolone antibiotic in rats. J Pharm Sci.,;86(5):550-3., 1997
  • Decreased oral availability of cyclosporin A at second administration in humans. Lee YJ, Chung SJ, Shim CK. Br J Clin Pharmacol.,44(4):343-5., 1997
  • Rectal absorption of omeprazole from suppository in humans. Choi MS, Chung SJ, Shim CK. J Pharm Sci.,85(8):893-4., 1996
  • Preparation and evaluation of proliposomes containing propranolol hydrochloride. Ahn BN, Kim SK, Shim CK. J Microencapsul.,12(4):363-75., 1995
  • Factors influencing the protein binding of YH-439 using an equilibrium dialysis technique. A new hepatoprotective agent. Lee WI, Yoon WH, Park JH, Lee JW, Shim CK, Lee MG. Biopharm Drug Dispos.,16(9):775-89., 1995
  • Nonlinear renal excretion of theophylline and its metabolites, 1-methyluric acid and 1,3-dimethyluric acid, in rats. Kuh HJ, Shim CK. Arch Pharm Res.,17(2):124-30., 1994
  • The pharmacokinetics of methotrexate after intravenous administration of methotrexate-loaded proliposomes to rats. Park JM, Ahn BN, Yoon EJ, Lee MG, Shim CK, Kim CK. Biopharm Drug Dispos.,15(5):391-407., 1994
  • Effect of cimetidine on the pharmacokinetics of fentiazac in rats. Kweon DS, Shim CK, Lee MH. J Pharm Sci.,82(9):952-5., 1993
  • Decreased systemic clearance of diltiazem with increased hepatic metabolism in rats with uranyl nitrate-induced acute renal failure. Lee YH, Lee MH, Shim CK. Pharm Res.,9(12):1599-606., 1992
  • Pharmacokinetic study of an iridoid glucoside: aucubin. Suh NJ, Shim CK, Lee MH, Kim SK, Chang IM. Pharm Res.,8(8):1059-63., 1991
  • Inter- and intrasubject variations of ranitidine pharmacokinetics after oral administration to normal male subjects. Shim CK, Hong JS. J Pharm Sci.,78(12):990-4., 1989
  • Dissolution of theophylline from sustained-release dosage forms and correlation with saliva bioavailability parameters. Chung BH, Shim CK. J Pharm Sci.,76(10):784-7., 1987
  • Estimation of renal blood flow by use of endogenous N1-methylnicotinamide in rats. Shim CK, Sawada Y, Iga T, Hanano M. J Pharmacobiodyn.,8(1):20-4., 1985
  • Estimation of renal secretory function for organic cations by endogenous N1-methylnicotinamide in rats with experimental renal failure. Shim CK, Sawada Y, Iga T, Hanano M. J Pharmacokinet Biopharm.,12(1):23-42., 1984
  • Effect of experimental acute renal failure on intrinsic renal tubular secretory clearance of organic cations in rats. Shim CK, Sawada Y, Iga T, Hanano M. J Pharmacobiodyn.,6(10):787-9., 1983
  • Prediction of renal tubular secretion of tetraethylammonium bromide by use of endogenous N1-methylnicotinamide in the rat. Shim CK, Sawada Y, Iga T, Hanano M. J Pharmacobiodyn.,5(7):534-7., 1982

국내전문학술지

  • Kim, S. B., & Kim, D. D., et al, (2018). Comparison of saline vs. blood replenishment after blood sampling in a rat pharmacokinetic study. Journal of Pharmaceutical Investigation, 1-9., 2018
  • Effect of tripolyphosphate (TPP) on the controlled release of cyclosporin A from chitosan-coated lipid microparticles. Ji-Woong Cheon, Chang-Koo Shim, Suk-Jae Chung and Dae-Duk Kim. J. Kor. Pharm. Sci. 39(1), 59-63 (2009), 2009
  • Hea-Kyoung Cho, Eun-Sook Lee, Jung-Won Lee, Jong-Kook Park, Jin-Hyoung Kang, Kyung-Shik Lee, Chang-Koo Shim, Suk-Jae Chung, Dae-Duk Kim, Hyo-Jeong Kuh, Clinical Pharmacokinetics of oxaliplatin and 5-fluorouracil administered in combination with leucovorin in Korean patients with advanced colorectal cancer. J Cancer Res Clin Oncol 132 : 320-326, 2006
  • J.H. Jang, J.K. Park, J.H. Kang, S.J. Chung, C.K. Shim, H.J. Kuh, Stability of 5-FU and Tegafur in Biological Fluids of Rats, J. Kor. Pharm. Sci. 34(3):161-168 (2004), 2004
  • J.S. Lee, M.H. Kang, M.K. Kim, M.K. Lee, S.J. Chung, C.K. Shim, Y.B. Chung, Pharmacokinetic Modeling and Simulation of the Carrier-Mediated Hepatic Transport of Organic Anions, YAKHAK HOEJI, Vol. 47, No 2, 110-119, 2003
  • D.S. Kim, I.W. Kim, S.J. Chung, C.K. Shim, Improved micrometric properties of pyridostigmine bromide, a highly hygroscopic drug, through microencapsulation., J. Kor. Pharm. Sci. 32(1):41-45, 2002
  • H.J. Kim, M.O.Yun, S.J. Lee, H.C. Choi, J.Y. Kim, I.W. Kim, C.K. Shim, S.J.Kang, A release test for gels containing ketoprofen., J. Kor. Pharm. Sci. 32(2):103-106, 2002
  • H.J. Yoo, M.K. Choi, K.S. Kim, S.J. Jung, C.K. Shim, Bioequivalence test of Shinil Cefadroxil capsule to Duricef capsule (cefadroxil 500 mg)., J. Applied Pharm. 10(4):303-308, 2002
  • M.K. Choi, M.H. Choi, K.S. Kim, I.H. Kim, Y.J. Lee, S.W. Myung, M.S. Kim, S.J. Chung, C.K. Shim, Bioequivalence of Dong Sung lovastatin tablet to Mevacor tablet (lovastatin 20 mg)., J. Kor. Pharm. Sci. 45:220-226, 2001
  • I.W. Kim, S.H. Lee, Y.M. Kim, S.Y. Jung, S.C. Kwon, S.J. Chung, C.K. Shim, Pharmacokinetics of Recombinant Human Granulocyte Colony Stimulating Factor (rhG-CSF) following Intravenous, Intramuscular and Subcutaneous Administration of HM10411 and Filgrastin to Rats and Mice., J. Kor. Pharm. Sci. 31:89-94, 2001
  • Y.J. Lee, Y.G. Kim, M.G. Lee, S.J. Chung, M.H. Lee, C.K. Shim, Analysis of bioequivalence study using log-transformed model., J. Kor. Pharm. Sci. 44:308-314, 2000
  • K. Yi, H.J. Kuh, S.J. Chung, M.H. Lee, C.K. Shim, Evaluation of a sample-pooling technique in estimating bioavaiability of compound for high-throuput lead optimazation., J. Kor. Pharm. Sci. 30:191-199, 2000
  • Y.H. Han, Y. B. Chung, K. Han, S.J. Chung, M. K. Park, C.K. Shim, Formulation and evaluation of tablets containing unsaponifiable fraction of Zea mays., J. Kor. Pharm. Sci. 44:578-587, 2000
  • S. J. Lee, J. K. Kim, M. O. Yun, H. J. Kim, C. K. Shim, K. R. Ze, Establishment of a release test reflecting in vitro skin permeation of nicotine from commercial patches., J. Kor. Pharm. Sci. 30:27-32, 2000
  • I.S. Song, S.J. Chung, C.K. Shim, Comparative study on the transport characteristics of canalicular liver plasma membrane vesicles prepared by two different methods., J. Kor. Pharm. Sci. 29:13-20, 1999
  • C.K. Shim, Guidline for bioequivalance studies for generic products in Japan., J. Kor. Pharm. Sci. 29:253-264, 1999
  • K.H. Yun, J.Y. Park, S.J. Park, E. H. Cho, J.M. Ryu, S.J. Chung, C.K. Shim, Bioequivalence evaluation of cisapride formulation proceded by Dong Wha Phamaceutical Co., J. Applied Pharm. 7:59-65, 1999
  • Y.J. Lee, M.G. Lee, S.J. Chung, M.H. Lee, C.K. Shim, Statistical analysis of three sequence-three periods bioequivalence study: Applicationj to bioequivalence test of ondansetron formulations., J. Kor. Pharm. Sci. 28:35-42, 1998
  • IW. Kim, T.G. Han, K.S. Kim, S.J. Chung, M.H. Lee, C.K. Shim, Bioequivalence of loxipen tablet to loxonin tablet.(Sodium Loxoprofen Anhydride 60 mg), J. Kor. Pharm. Sci. 28:185-191, 1998
  • Y.J. Lee, C.K. Shim, Development of K-BEtest, a computer program for the analysis of bioequivalence., J. Kor. Pharm. Sci. 28 (4): 223-229, 1998
  • K.R. Ze, J.K. Kim, S.J. Lee, S.C. Choi, H.J. Kim, H.S. Ko, O.J. Paek, C.K. Shim, D.C. Moon, Studies on the Quality Control and Evaluation Methods of Advanced Dosage Forms (II)- The Vaporising mats., The Annual Report of KFDA, 2:208~215, 1998
  • K.R. Ze, J.K. Kim, S.J. Lee, M.O. Yun, H.J. Kim, J.H. Hong, C.K. Shim, Studies on the quality control and evaluation methods of advanced dosage forms(I)., J. N.I.H. Kor., in press., 1997
  • Y.J. Lee, S.J. Chung, M.H. Lee, C.K. Shim, Proliposomal Clenbuterol Patch for Transderinal Delivery, J. Kor. Pharm. Sci. 27:303-311, 1997
  • 이정욱 (Jeong Uk Lee ) 정석재 (Seok Jae Chung ) 이민화 (Min Hwa Lee ) 심창구 (Chang Koo Shim ), Dermal Absorption and Body Distribution of 125I-rhEGF in Hairless Mice, YAKHAK HOEJI, Vol. 41, No 6, 737-748, 1997
  • 이정욱 (Jeong Uk Lee ) 정석재 (Suk Jae Chung ) 이민화 (Min Hwa Lee ) 심창구 (Chang Koo Shim ), Body Distribution of 125I-rhEGF Across Normal and Damaged Rat Skins, YAKHAK HOEJI, Vol. 41, No 6, 730-736, 1997
  • 고여욱 (Yeo Wook Koh ) 남권호 (Kouen Ho Nam ) 정주영 (Ju Young Jung ) 박승국 (Seung Kook Park ) 유영효 (Young Hyo Yu ) 김재환 (Jae Hwan Kim ) 한건 (Kun Han ) 박명환 (Myung Hwan Park ) (Chang Koo Shim ), in vivo and in vitro Metabolism of Recombinant Human Epidermal Growth Factor (DWP401) in Rats, YAKHAK HOEJI, Vol. 41, No 3, 381-388, 1997
  • 정주영 (Joo Young Chung ) 고여욱 (Yeo Wook Koh ) 남권호 (Kwon Ho Nam ) 조재열 (Jae Youl Cho ) 박승국 (Seung Kook Park ) 유영효 (Young Hyo Yu ) 김재환 (Jae Hwan Kim ) 한건 (Kun Han ) (Chang Koo Shim ), Pharmacokinetics Of Recombinant Human Epidermal Grouth Factor (DWP401) in Rats, YAKHAK HOEJI, Vol. 41, No 3, 328-334, 1997
  • 김경호 (Kyeong Ho Kim ) 박우선 (Woo Sun Park ) 심창구 (Chang Gu Shim ), Determination of beta-sitosterol in Unsaponifiable Fraction of Zea mays and Related Drug Preparations by HPLC, YAKHAK HOEJI, Vol. 40, No 2, 149-154, 1996
  • A.R. Cho, J.U. Lee, B.L. Ahn, J.Y. Chung, Y.W. Koh, C.K. Shim, Percutaneous Absorption of Recombinant h-EGF through Normal, Stripped and First-Degree Burn Skin, J. Kor. Pharm. Sci. 26(1):29-32, 1996
  • E.J. Yang, W.B. Kim, C.K. Shim, M.H. Lee, S.J. Chung, Pharmacokinetic Study of Tianxian, Anticancer Preparation Originated from Natural Sources, Seoul University Journal of Pharmaceutical Science, Vol. 20, 32-39, 1995
  • S.H. Lee, M.K. Kim, Y.H. Han, C.K. Shim, Damage of Ibuprofen Suppository on Rectal Mucosa of Rats, J. Kor. Pharm. Sci. 24:115-129, 1994
  • M.K. Chang, S.B. Han, K.K. Kim, S.H. Son, C.K.Shim, The Effects of Tetracycline-containing Gel on Gingival Crevicular Enzyme Activity, 대한 치주과학회지 : Vol. 24, No. 3, 1994
  • H.S. Cheong, S.B. Han, S.W. Nam, C.K. Shim, S.B. Kye, Antimicrobial Activities of Root Surfaces treated with Tetracycline-containing Gel and a Maxture of tetracycline and citric acid-containing gel : in vivo study, 대한 치주과학회지, 1994
  • S.B. Han, J.I. Lee, J.M. Heo, M.K. Chang, C.K. Shim, C.W. Lee, Topical Application of Tetracycline Gel in Scaling and Root Planing, 대한 치주과학회지 (Journal of Periodontal & Implant Science), 1994
  • C.K. Shim, E.J. Choi, S.W. Lee, D.O. Kim, N.J. Park, Y.S. Kang, Y.H. Yu, Pharmacokinetic study on DWC-751, a new cephalosporin, in rats and mice., J. Appl. Pharmacol., 2, 204-210, 1993
  • S.H. Lee, M.K. Kim, Y.H. Han, C.K. Shim, Damage of ibuprofen suppository on rectal mucosa of rats., J. Kor. Pharm. Sci., 24, 115-129, 1993
  • C.K. Shim and J.S. Oh, Sustained absorption of drugs by extending gastrointestinal transit time., Seoul Univ. J. Pharm. Sci., 18, 37-58, 1993
  • C.K. Shim, Y.H. Han. J.S. Woo and C.H. Lee, Effect of arginine or sodium phosphate dibasic on the stability of omeprazole in aqueous solution., J. Kor. Pharm. Sci., 23, 225-229, 1993
  • K.H. Park, M.J. Kim, M.G. Lee, C.K. Shim and M.H. Lee, Relationship between plasma concentrations of haloperidol and its metabolite, reduced haloperidol, and clinical response in Schizophrenia., J. Kor. Pharm. Sci., 23, 165-177, 1993
  • H.J. Kim, Y.H. Han and C.K. Shim, Damage of omeprazole suppository on rectal mucosa of rats., J. Kor. Pharm. Sci., 23, 127-132, 1993
  • C.K. Shim and S.H. Yeo, Albumin-crosslinked PVP hydrogel as a gastric retension platform., J. Kor. Pharm. Sci., 23, 145-153, 1993
  • C.K. Shim, Y.H. Han. J.S. Woo and C.H. Lee, Effect of arginine or sodium phosphate dibasic on the stability of omeprazole in aqueous solution., J. Kor. Pharm. Sci., 23, 225-229, 1993
  • K.H. Park, M.J. Kim, M.G. Lee, C.K. Shim and M.H. Lee, Relationship between plasma concentrations of haloperidol and its metabolite, reduced haloperidol, and clinical response in Schizophrenia., J. Kor. Pharm. Sci., 23, 165-177, 1993
  • H.J. Kim, Y.H. Han and C.K. Shim, Damage of omeprazole suppository on rectal mucosa of rats., J. Kor. Pharm. Sci., 23, 127-132, 1993
  • C.K. Shim and S.H. Yeo, Albumin-crosslinked PVP hydrogel as a gastric retension platform., J. Kor. Pharm. Sci., 23, 145-153, 1993
  • C.K. Shim, C.S. Oh and B.C. Shin, Swelling and release characteristics of PVP hydrogel polymerized by gamma -irradiation method., J. Pharm. Soc. Kor., 36, 511-519, 1993
  • M.H. Kim, C.K. Shim, I.M. Chang, Different pharmacokinetics of aucubin in rats of carbon tetrachloride and D-galactosamine-induced hepatic failure., J. Pharm. Soc. Kor., 36, 383-388, 1993
  • S.N. Jeong, S.B. Han, S.H. Son, C.K. Shim, The adjunctive effects of tetracycline and a mixture of tetracycline and citric acid gel on non-surgical periodontal therapy., J. Kor. Acad. Periodontol., 22, 499-513, 1992
  • Y.B. Lee, I.B. Koh, C.K. Shim, S.K. Kim, M.H. Lee, Effect of phenobarbital on the metabolite kinetics of diltiazem in rats., J. Kor. Pharm. Sci., 22, 301-306, 1992
  • Y.H. Lee, C.K. Shim, M.H. Lee, S.K. Kim, HPLC determination of diltiazem and deacetyldiltiazem in rat plasma., J. Kor. Pharm. Sci., 22, 317-321, 1992
  • S.B. Han, C.K. Shim, J.I.. Lee, C.W. Lee, J.M. Shim, The effect of citric acid gel application on soft tissue healing following scaling and root planing., J. Kor. Acad. Periodontol., 22, 1-7, 1992
  • C.K. Shim, B.Y. Hwang, B.N. Ahn, M.H. Lee, C.K. Kim, S.K. Kim, Iontophoretic transdermal transport of propranolol hydrochloride through rat skin in vitro. Seoul Univ. J. Pharm. Sci., 17, 6-10, 1992
  • C.K. Shim, C.K. Kim, M.H. Lee, S.K. Kim, Development of controlled release oral drug delivery system by membrane-coating III. Preparation of theophylline tablets and pharmacokinetic evaluation in man., J. Kor. Pharm. Sci., 22, 205-210, 1992
  • K.H. Park. M.H. Lee, C.K. Shim, M.G. Lee, J.S. Park, Simultaneous determination of haloperidol and irs metabolite, reduced haloperidol, in plasma by gas chromatography using nitrogen phosphorous selective detection., J. Kor. Pharm. Sci., 22, 197-204, 1992
  • C.K. Shim, C.Y. Lee, C.K. Kim, Development of target-specific drug delivery systems using glycosylated proliposome 1. Binding of asialofetuin-labeled liposomes to lectin RCA., J. Kor. Pharm. Sci., 22, 155-161, 1992
  • J.J. Kim, S.C. Chi, C.K. Shim, C.K. Kim, Effect of Tween 20 on the penetration of ketoprofen through excised rat skin., J. Kor. Pharm. Sci., 22, 163-166, 1992
  • C.K. Shim, Y.M. Lee, S.H. Yeo, Swelling and proxyphylline release kinetics of enzyme-digestible swelling hydrogel tablet.., J. Pharm. Soc. Kor., 36, 212-219, 1992
  • C.K. Shim, H.W. Lee, Mechanisms of multiple peak phenomenon in the plasma profile of drugs following oral administration., J. Kor. Pharm. Sci., 21, 201-213, 1991
  • C.K. Shim, Y.H. Han, D.S. Kwon, Comaprative study of particulate contamination from ampoule and prefilled syringe., J. Kor. Pharm. Sci., 21, 155-160, 1991
  • M.S. Seo, C.K. Shim, J.B. Kwon, D.S. Na, S.B. Lee, K.S. Hahm, M.H. Han, Pharmacokinetic preformulation study of rH IL-2., Korean J. BRM., 1, 25-30, 1991
  • M.S. Seo, C.K. Shim, J.B. Kwon, D.S. Na, S.B. Lee, K.S. Hahm, M.H. Han, Preformulation study of IL-2 for controlled release implant., Korean J. BRM., 1, 31-33, 1991
  • H.J. Kuh, C.K. Shim, M.H. Lee, S.K. Kim, HPLC assay and renal excretion characteristics of theophylline and its metabolites in rat., J. Kor. Pharm. Sci. 21, 33 - 41, 1991
  • C.W. Lee, S.M. Choi, C.K. Shim, S.B. Han, The effect of citric acid gel on retained plaque, calculus and root surface., The J. Kor. Acad. Periodentol. 20, 385 - 398, 1990
  • H.A. Ahn, C.K. Shim, Iontophoretic drug delivery through the skin., Seoul Univ. J. Pharm. Sci. 15, 79 - 99, 1990
  • Y.H. Han, C.K. Shim, Albumin-mediated hepatic uptake of drugs., J. Kor. Pharm. Sci. 20, 179 -192, 1990
  • C.K. Shim, Manufacture and quality control of rubber stoppers for injections. Proceedings of the 8th Seminar on "Pharmaceutical Technology", July 31 by Korean Pharmaceutical Society 69 - 87, 1990
  • M.S. Suh, C.K. Shim, J.B. Kwon, D.S. Na, S.B. Lee, K.S. Hahm, M.H. Han, Pharmacokinetic preformulation study of rH IL-2., J. Pharm. Soc. Kor. 34, 238 -243, 1990
  • M.J. Lee, C.K. Shim, M.H. Lee, S.K. Kim, Pharmacokinetics of praziquantel in rabbits., J. Pharm., Soc. Kor., 34, 40 - 46, 1990
  • C.K. Shim, M.A. Kim, M.H. Lee, S.K. Kim, Development of controlled release oral drug delivery systems by membrane-coating technique II. Correlation between saliva and plasma concentration of acetaminophen in man., J. Kor. Pharm. Sci., 20, 29 -33, 1990
  • J.M. Yu, C.K.Shim, M.H. Lee, S.K. Kim, Dissociation of Chlorpheniramine Mallate(CPM) from Sustained-Release Tablets Containing CPM in the Coated Film Layer, J. Kor. Pharm. Sci., Vol.20, No.2, 89-95, 1990
  • C.K. Shim, H.L. Kwon, C.K. Lee, I.S. Han, K.S. Choi, Bioequivalence test of slow-release theophylline dosage forms using saliva samples., J. Kor. Pharm. Sci., 19, 191-194, 1989
  • C.K. Shim, Effect of pharmaceutical excipients on the efficacy and safety of drugs. Proceedings of the Science Month-Commemorial Symposium on "Pharmaceutical Excipients in the Development of Dosage Forms", April 21, Korean Pharmaceutical Society. 11-24, 1988
  • D.S. Jeong, C.K. Shim, M.H. Lee, S.K. Kim, Manufacturing and evaluation of proliposomes., J. Pharm. Soc. Kor., 32, 234 -238, 1988
  • D.D. Kim, C.K. Shim, Decrease in hepatic metabolism of antipyrine by uranylnitrate-induced experimental acute renal failure in the rat., Kor. Biochem. J., 21, 1- 8, 1988
  • 정대식 (Dae Sik Chung ) 심창구 (Chang Koo Shim ) 이민화 (Min Hwa Lee ) 김신근 (Shin Keun Kim ), Preparation and Evaluation of Proliposome, YAKHAK HOEJI, Vol. 32, N0. 4, 234-238, 1988
  • D.D. Kim, C.K. Shim, 질산우라늄으로 유발시킨 실험적 급성 신장해에 의한 간장의 안티피린 대사 기능 저하, Kor. Biochem. J. Vol. 21, No. 1, 1-8, 1988
  • C.K. Shim, Characteristics of some animal models of experimental renal failure., J. Kor. Pharm. Sci., 17, 205 -211, 1987
  • J.S. Han, C.K. Shim, M.H. Lee, S.K. Kim, Dissolution and rectal absorption of acetaminophen from suppositories., J. Pharm. Soc. Kor., 31, 286 - 295, 1987
  • C.K. Shim, D.D. Kim, H.S. Kim, I.W. Jung, M.Y. Yoo, Pharmacokinetic study of recombinant human interferon alpha A in rats., Kor. Biochem. J., 20, 103 -107, 1987
  • C.H. Kim, C.K. Shim, M.H. Lee, S.K. Kim, Preparation of furosemide retard tablet using hydroxyethylcellulose as matrix forming material., J. Kor. Pharm. Sci., 17, 47 - 53, 1987
  • T.Y. Cho, C.K. Shim, M.H. Lee, S.K. Kim, Effect of blended Chinese traditional medicine, Ssanghwa-Tang, on hepatic clearance of sulfobromophthalein in rats., J. Kor. Pharm. Sci., 17, 89 - 93, 1987
  • Y.K. Suh, C.K. Shim, M.H. Lee, S.K. Kim, Effect of alcohol infusion on the pharmacokinetics of acetaminophen and antipyrine in rats., Seoul Univ. J. Pharm. Sci., 11, 51 - 59, 1986
  • S.S. Lee, C.K. Shim, M.H. Lee, S.K. Kim, Dose-dependent pharmacokinetics of acetaminophen in the rats., J. Pharm. Soc. Kor., 30, 301-305, 1986
  • C.K. Shim, S.J. Chung, Effect of sodium taurodeoxycholate on biliary excretion of amaranth as an anioic model drug in rats., J. Kor. Pharm. Sci., 16,110 -117, 1986
  • C.K. Shim, D.D. Kim, I.W. Jung, H.S. Kim, M.Y. Yoo, Absorption of α-interferon from ointment after topical application to nude mice and rats., J. Kor. Pharm. Sci., 16, 118 -123, 1986
  • C.K. Shim, S.J. Chung, J.U. Lee, M.H. Lee, S.K. Kim, Effect of bile salt on pharmacokinetics of bretylium in the rat (1)., Arch. Pharm. Res., 9, 111-114, 1986
  • Y.B. Chung, C.K. Shim, M.H. Lee, S.K. Kim, Effect of a Chinese herbal remedy, Ssanghwa-Tang, on distribution and elimination of drugs in rats., Kor. Biochem. J., 19, 18 -24, 1986
  • O.S. Kwon, C.K. Shim, M.H. Lee, S.K. Kim, Effect of sodium taurodeoxycholate on the disposition and elimination of methylene blue in the rats of experimental hepatic failure., J. Pharm. Soc. Kor., 30, 68 -72, 1986
  • C.K. Shim, Effect of ion-pair complexation with bile acid on the biliary excretion and systemic distribution of organic cationic drugs., Arch. Pharm. Res., 9, 49 -54, 1986
  • M.C. Kim, C.K. Shim, M.H. Lee, S.K. Kim, Preparation and evaluation of sustained-release aspirin agglomerates., Seoul Univ. J. Pharm. Sci., 10, 201-208, 1985
  • C.K. Shim, D.D. Kim, I.W. Jung, U. Chang, H.S. Kim, M.Y. Yoo, Pharmacokinetic study of α-interferon administered intravenously and topically in experimental animals., J. Kor. Soc. Virol., 15, 91- 97, 1985
  • C.K. Shim, J.U. Lee, Comparative study of rifampicin pharmacokinetics administered orally and intravenously in the fasted and non-fasted rats., Arch. Pharm. Res., 8, 177 -186, 1985
  • H.J. Lee, M.H. Lee, C.K. Shim, Preparation and evaluation of ethylcellulose microcapsules of indomethacin., Arch. Pharm. Res., 7, 33 - 40, 1984
  • S.R. Oh, S.K. Kim, C.K. Shim, D.C. Kim, Study on the comparative bioavailability of acetaminophen in soft capsule and hard capsule., Seoul Univ. J. Pharm. Sci., 9, 10 -19, 1984
  • B.N. Ann, S.K. Kim, C.K. Shim, Y.B. Chung, Effects of a Chinese traditional medicine, Ssanghwa-Tang, on the harmacokinetics of sulfobromophthalein in the rats of hepatic failure induced by carbon tetrachloride., J. Pharm. Soc. Kor., 28, 207 -215, 1984
  • S.Y. Lee, S.C. Shin, M.H. Lee, C.K. Shim, Effect of diethylphthalate on the release of salicylic acid from ethylcellulose films., J. Pharm. Soc. Kor., 28, 169 -177, 1984
  • C.K. Shim, S.J. Chung, Curve fitting in pharmacokinetics through MULTI program for microcomputers., Seoul Univ. J. Pharm. Sci., 8, 37 - 47, 1983
  • C.K. Shim, J.H. Lee, Targeting of drugs especially by liposomes., J. Kor. Pharm. Sci., 13, 153 -172, 1983
  • C.K. Shim, Effect of true partition coefficient on the determination of extraction coefficient of ion-pair complexes., J.Pharm. Soc. Kor., 27, 125 -131, 1983
  • C.K. Shim, Decrease of distribution volume of a basic drug in rats of experimental renal failure., J. Pharm. Soc. Kor., 27, 21 - 28, 1983
  • C.K. Shim, Studies on acid-base indicators in the mixture of some solvents (II)., J. Health Fell. Found., 7,, 1981
  • W.K. Lee, B.K. Kim, C.K. Shim, Detection of N,N-dimethylaniline in ampicilline trihydrate by thin layer chromatography and densitometry., J. Pharm. Soc. Kor., 22, 238 -241, 1978
  • W.K. Lee, K.S. Yu, C.K. Shim, Studies on the colorimetric determina-tion of drugs with phosphomolybdic acid (II). Determination of amoxicillin., J. Pharm. Soc. Kor., 21, 27 - 29, 1977
  • W.K. Lee, B.K. Kim, K.S. Yu, C.K. Shim, Studies on the utilization of coloring constituents of Lithospermi Radix (I). Dissociation constant of shikonin and its analytical application., Seoul Univ. J. Pharm. Sci., 2, 36 - 42, 1977
  • W.K. Lee, C.K. Shim, Studies on acid-base indicators in the mixtures of some solvents (I). Determination of ampicillin, amoxicillin and cephalexin in aqueous organic solvents., J. Pharm. Soc. Kor., 20, 32 -36, 1976

특허

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    • 출원번호 : PCT/KR2015/001503 (2015.02.13)
    • 출원인 : 서울대학교 산학협력단
    • 발명인 : 정석재, 노치경, 김석중, 2015
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    • 출원번호 : 10-2014-0017017 (2014.02.14)
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    세포전달시스템용 다공성 히아루론산 스펀지의 제조방법
    • 등록번호 : 0689107호 (2007.02.23)
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    • 발명인 : 구효정, 이정원, 김성윤, 심창구, 정석재, 2009, 2007
  • 진세노사이드 가수분해물을 함유하는 퇴행성 뇌질환의 예방 및 치료용 조성물
    • 등록번호 : 0448667호 (2004.09.03)
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    • 발명인 : 묵인희, 정민환, 정석재, 2004, 2004

저서

  • 기타,약제학분과회(이범진, 신영희, 정서영, 손영택, 전인구, 강진양, 심창구, 정석재, 김대덕, 지상철, 김진석, 용철순, 양재헌, 손동환, 이화정, 사홍기, 이용복, 최준식, 최영욱, 이재휘, 지웅길, 김동출, 한건, 정연복),생물약제학과 약물속도론 (약제학총서 3) ,도서출판 신일상사, 2005
  • 제제공학 편찬위원회(김길수, 박경호, 서성훈, 손동환, 손영택, 용철순, 전인구, 정석재, 정연복, 최영욱, 최우식, 최후균, 황성주), 제제공학 ,도서출판 신일상사, 1999
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