• 정석재 (鄭晳在)
• 직위 교수
• 전공 약제학
• 전화 02-884-3170
• 팩스 02-885-8317
• 메일 sukjae@snu.ac.kr
• 주소 서울대학교 약학대학 21동 317호

학력

주요관심연구분야

1. Pharmacokinetic analysis를 이용한 약물의 disposition 특성에 관한 연구
2. Biopharmaceutics실험방법에 의한 흡수, 배설 및 대사 mechanism에 관한 연구
3. Disease state에서의 약물 pharmacokinetics의 변화에 관한 연구

대표논문자료

• Kim MH, Maeng HJ, Yu KH, Lee KR, Takashi Tsuruo, Kim DD, Shim CK, Chung SJ, Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain J Pharm Sci 99, pp. 1548-1566 (2010)
• Yu KH, Lee YR, Ahn SH, Kim DD, Shim CK, Chung SJ, Contribution of a significant first-pass effect of dimethyl-4,4 '-dimethoxy-5,6,5 ',6'-dimethylene dioxybiphenyl-2,2 '-dicarboxylate in the liver to its poor bioavailability in rats. JOURNAL OF PHARMACY AND PHARMACOLOGY 61, pp. 1197-1203 (2009.09)
• Yin YM, Cui FD, Kim JS, Choi MK, Choi BC, Chung SJ, Shim CK, Kim DD, Preparation, characterization and in vitro intestinal absorption of a dry emulsion formulation containing atorvastatin calcium. DRUG DELIVERY 16, pp. 30-36 (2009.11)
• Jin HE, Hong SS, Choi MK, Maeng HJ, Kim DD, Chung SJ, Shim CK, Reduced antidiabetic effect of metformin and down-regulation of hepatic oct1 in rats with ethynylestradiol-induced cholestasis. PHARMACEUTICAL RESEARCH 26(3), pp. 549-559 (2009.11)
• Yang R, Yang SG, Shim WS, Cui FD, Cheng G, Kim IW, Kim DD, Chung SJ, Shim CK, Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates. JOURNAL OF PHARMACEUTICAL SCIENCES 98(3), pp. 970-984 (2009.11)
• Lee JH, Woo YA, Hwang IC, Kim CY, Kim DD, Shim CK, Chung SJ, Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 50, pp. 872-877 (2009.11)
• Jin QR, Shim WS, Choi MK, Tian GY, Song IS, Yang SG, Kim DD, Chung SJ, Shim CK, Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp. XENOBIOTICA 39, pp. 711-721 (2009.11)
• Lee SH, Oh T, Jeon BY, Kwak EY, Shim WS, Cho SN, Kim DD, Chung SJ, Shim CK, Tissue-specific changes in mRNA expression of Abc and Slc transporters in murine pulmonary tuberculosis. XENOBIOTICA 39, pp. 738-748 (2009.11)
• Shim WS, Park JH, Ahn SJ, Han L, Jin QR, Li H, Choi MK, Kim DD, Chung SJ, Shim CK, Testosterone-independent down-regulation of oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: Effects on distribution of a model organic cation, tetraethylammonium. JOURNAL OF PHARMACEUTICAL SCIENCES 98, pp. 739-747 (2009.11)
• Yin YM, Cui FD, Mu CF, Choi MK, Kim JS, Chung SJ, Shim CK, Kim DD, Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation. JOURNAL OF CONTROLLED RELEASE 140, pp. 86-94 (2009.12)
• Hwang, SM/Kim, DD/Chung, SJ/Shim, CK, Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis. JOURNAL OF CONTROLLED RELEASE 129, pp. 100-106 (2008.07)
• Shim WS, Park JH, Ahn SJ, Han L, Jin QR, Li H, Choi MK, Kim DD, Chung SJ, Shim CK, Testosterone-independent down-regulation of Oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: Effects on distribution of a model organic cation, tetraethylammonium. JOURNAL OF PHARMACEUTICAL SCIENCES, (2008.05)
• Li, H/Jin, HE/Kim, W/Han, YH/Kim, DD/Chung, SJ/Shim, CK, Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells. PHARMACEUTICAL RESEARCH 25, pp. 2601-2612 (2008.01)
• Yang R, Yang SG, Shim WS, Cui F, Cheng G, Kim IW, Kim DD, Chung SJ, Shim CK, Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates. JOURNAL OF PHARMACEUTICAL SCIENCES, (2008.01)
• Jin HE, Hong SS, Choi MK, Maeng HJ, Kim DD, Chung SJ, Shim CK, Reduced antidiabetic effect of metformin and down-regulation of hepatic OCT1 in rats with ethynylestridiol-induced cholestasis. PHARMACEUTICAL RESEARCH, (2008.01)

관심연구분야